Fantasy Defense Rankings Week 10: Who to start, sit at D/ST in fantasy football


Our Week 10 fantasy defense rankings feature most of the usual studs at the top, but the sleeper D/STs that always emerge are tougher to pin down that usual. Not only are several favorable matchups out because of byes, but a few more potential waiver wire streamers hang in the balance while we wait to see who starts at quarterback for couple teams. 

Fortunately, only one D/ST, Cincinnati, that’s even a semi-regular start is off this week because of byes. No one will miss the Giants, Texans, or Bears’ defenses, but we’ll certainly miss being able to play D/STs against those offenses. That takes away at least a few high-end options and potential sleepers.

Quarterback | Running back | Wide receiver | Tight end | Kicker

There are still several favorable matchups; unfortunate, most go to D/STs that are already owned in the majority of leagues.  This likely means fewer owners will need to hit the waiver wire to find a streaming option, but if you’re in the group that does, you could try the Eagles (@ Broncos), Raiders (vs. Chiefs), or Titans (vs. Saints).

Quarterback | Running back | Wide receiver | Tight end | Kicker

Of course, the Titans’ sleeper status probably depends on who’s starting under center for New Orleans. Taysom Hill isn’t a great passer, but his running ability limits potential sack and INT opportunities for defenses. Tennessee isn’t an overly strong defense, so it really needs the big-play opportunities that Trevor Siemian is more likely to provide. The same is true for the Packers (vs. Seahawks), who would vault into the top 10 if Geno Smith is starting in place of Russell Wilson (finger) again. The Seahawks themselves would jump up into streamer territory if Jordan Love is starting in place of Aaron Rodgers (reserve/COVID list) again.

Perhaps no defense would see a bigger shift in rankings based on opposing QBs than Carolina (@ Cardinals). If Kyler Murray (ankle) starts, the Panthers are virtually unusable despite several big weeks this year. If Colt McCoy is under center, Carolina has top-10 upside. For now, we’re expecting Murray to start, but stay on top of that throughout the week. 

There aren’t too many regular starters knocked out of consideration by tough matchups. Miami and San Francisco saw upticks in ownership levels last week, but with matchups against the Ravens and Rams, respectively, neither should be considered this week. New Orleans (@ Titans) is also in a tough spot, but a Derrick Henry-less Tennessee offense isn’t nearly as scary.

There are plenty of good D/ST options this week, but there could be even more depending on injury news. Be ready to upgrade if the opportunity presents itself, even if that means carrying two D/STs for part of the week. 

Note: We’ll be updating these D/ST rankings throughout the week, so check back for the latest analysis and player movement.

Fantasy Defense Rankings Week 10: Who to start, sit at D/ST in fantasy football

Rank Team
1 Buffalo Bills @ NYJ
2 Tampa Bay Buccaneers @ WAS
3 Indianapolis Colts vs. JAX
4 Pittsburgh Steelers vs. DET
5 New England Patriots vs. CLE
6 Los Angeles Rams @ SF
7 Cleveland Browns @ NE
8 Arizona Cardinals vs. CAR
9 Baltimore Ravens @ MIA
10 Dallas Cowboys vs. ATL
11 Philadelphia Eagles @ DEN
12 Las Vegas Raiders vs. KC
13 Tennessee Titans vs. NO
14 New Orleans Saints @ TEN
15 Green Bay Packers vs. SEA
16 Carolina Panthers @ ARI
17 Los Angeles Chargers vs. MIN
18 Miami Dolphins vs. BAL
19 Denver Broncos vs. PHI
20 Minnesota Vikings @ LAC
21 Detroit Lions @ PIT
22 San Francisco 49ers vs. LAR
23 Seattle Seahawks @ GB
24 Jacksonville Jaguars @ IND
25 Kansas City Chiefs @ LV
26 Atlanta Falcons @ DAL
27 New York Jets vs. BUF
28 Washington Football Team vs. TB

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